"He [Jesus] took Peter, James, and John along with him, and he began to be deeply distressed and troubled. 'My soul is overwhelmed with sorrow to the point of death,' he said to them."
You know those times when your soul is so impregnated with pain it feels like it is about to burst? In these moments you realize your body is unaccustomed to such pain and it's too finite and weak to deal with the sorrow. Desperately, you try to release the pain, to let your soul somehow seep out of your body to a place where it can expand with the grief that overwhelms it. But such attempts are futile. Your body and your soul are inexplicably intertwined. You cannot escape your pain.
Jesus knows how that feels.